localPP {BasketTrial} | R Documentation |
Local Power Prior for Bayesian Basket Trial
Description
Local Power Prior for Bayesian Basket Trial
Usage
localPP(
nDat,
yDat,
be.a0 = NULL,
be.b0 = NULL,
a = 1,
delta = 0.4,
method = "PEB",
symmetry = FALSE
)
Arguments
nDat |
a vector of length B for the sample size in each basket. |
yDat |
a vector of length B for the number of responses in each basket. |
be.a0 |
a vector of length B for beta prior parameter a0 in each basket. |
be.b0 |
a vector of length B for beta prior parameter b0 in each basket. |
a |
the global control parameter in the local PP 3-component framework. |
delta |
the threshold parameter in the local PP 3-component framework. |
method |
either |
symmetry |
logical variable to indicate whether the similarity matrix
will be set to be symmetric; default is |
Value
It returns a list including the posterior beta parameters and similarity matrix.
References
Zhou, H., Shen, R., Wu, S., & He, P. (2023). A Bayesian Basket Trial Design Using Local Power Prior. arXiv preprint arXiv:2312.15352.
Examples
localPP(nDat = c(25, 25, 25, 25, 25), yDat = c(2,9,11,13,20),
be.a0 = rep(0.5, 5), be.b0 = rep(0.5, 5), a = 4, delta = 1, method = "PEB")