macula_rwe {jarbes} | R Documentation |
Meta-analysis: 83 observational studies assessing the effectiveness of intravitreal therapy for diabetic maculaedema
Description
Meta-analysis of 83 studies comparing 12-month visual acuity change results in routine clinical practices of intravitreal therapy for diabetic maculaedema (DME) to the change in RCTs by pooling data published in the last decade on treated eyes of treatment effect from OS.
Format
A dataframe with 83 rows and 13 columns. Each row represents study results, the columns are:
- therapy
Used Medication
- author_year
Author and year.
- eyes
Number of tested eyes.
- TE
Mean Change in Visual Acuity after 12-Months. Where Visual Acuity is measured in VAR (Visual Acuity Rating) score
- seTE
Standard Error of the Treatment Effect
- lower_95pct_ci
Lower 95prc CI for TE
- upper_95pct_ci
Upper 95prc CI for TE
- number_of_patients_at_baseline
Number of Patients in Study at Baseline
- mean_age
The mean age of patients per study
- baseline_va
Mean Visual Acuity at Baseline. Where Visual Acuity is measured in VAR (Visual Acuity Rating) score
- 12_month_va
Mean Visual Acuity after 12 months. Where Visual Acuity is measured in VAR (Visual Acuity Rating) score
- baseline_cst
Mean Central Subfield Thickness at Baseline
- 12_month_cst
Mean Central Subfield Thickness after 12 months
Source
Mehta H, Nguyen V, Barthelmes D, Pershing S, Chi GC, Dopart P, Gillies MC. Outcomes of Over 40,000 Eyes Treated for Diabetic Macula Edema in Routine Clinical Practice: A Systematic Review and Meta-analysis. Adv Ther. 2022 Dec;39(12):5376-5390. doi: 10.1007/s12325-022-02326-8. Epub 2022 Oct 15. PMID: 36241963; PMCID: PMC9618488.