optimal_multitrial_generic {drugdevelopR} | R Documentation |
Generic function for optimizing multi-trial programs
Description
Generic function for optimizing multi-trial programs
Usage
optimal_multitrial_generic(case, strategy = TRUE)
Arguments
case |
choose case: "at least 1, 2 or 3 significant trials needed for approval" |
strategy |
choose strategy: "conduct 1, 2, 3 or 4 trials in order to achieve the case's goal"; TRUE calculates all strategies of the selected |
Effect sizes
In other settings, the definition of "small", "medium" and "large" effect
sizes can be user-specified using the input parameters steps1
, stepm1
and
stepl1
. Due to the complexity of the multitrial setting, this feature is
not included for this setting. Instead, the effect sizes were set to
to predefined values as explained under sProg1, sProg2 and sProg3 in the
Value section.
[Package drugdevelopR version 1.0.2 Index]