%global __brp_check_rpaths %{nil} %global __requires_exclude ^libmpi %global packname CNVreg %global packver 1.0 %global rlibdir /usr/local/lib/R/library Name: R-CRAN-%{packname} Version: 1.0 Release: 1%{?dist}%{?buildtag} Summary: CNV-Profile Regression for Copy Number Variants Association Analysis with Penalized Regression License: GPL-3 URL: https://cran.r-project.org/package=%{packname} Source0: %{url}&version=%{packver}#/%{packname}_%{packver}.tar.gz BuildRequires: R-devel >= 4.1.0 Requires: R-core >= 4.1.0 BuildArch: noarch BuildRequires: R-stats BuildRequires: R-CRAN-Matrix BuildRequires: R-CRAN-doParallel BuildRequires: R-CRAN-dplyr BuildRequires: R-CRAN-foreach BuildRequires: R-CRAN-glmnet BuildRequires: R-CRAN-tidyr Requires: R-stats Requires: R-CRAN-Matrix Requires: R-CRAN-doParallel Requires: R-CRAN-dplyr Requires: R-CRAN-foreach Requires: R-CRAN-glmnet Requires: R-CRAN-tidyr %description Performs copy number variants association analysis with Lasso and Weighted Fusion penalized regression. Creates a "CNV profile curve" to represent an individual’s CNV events across a genomic region so to capture variations in CNV length and dosage. When evaluating association, the CNV profile curve is directly used as a predictor in the regression model, avoiding the need to predefine CNV loci. CNV profile regression estimates CNV effects at each genome position, making the results comparable across different studies. The penalization encourages sparsity in variable selection with a Lasso penalty and encourages effect smoothness between consecutive CNV events with a weighted fusion penalty, where the weight controls the level of smoothing between adjacent CNVs. For more details, see Si (2024) . %prep %setup -q -c -n %{packname} # fix end of executable files find -type f -executable -exec grep -Iq . {} \; -exec sed -i -e '$a\' {} \; # prevent binary stripping [ -d %{packname}/src ] && find %{packname}/src -type f -exec \ sed -i 's@/usr/bin/strip@/usr/bin/true@g' {} \; || true [ -d %{packname}/src ] && find %{packname}/src/Make* -type f -exec \ sed -i 's@-g0@@g' {} \; || true # don't allow local prefix in executable scripts find -type f -executable -exec sed -Ei 's@#!( )*/usr/local/bin@#!/usr/bin@g' {} \; %build %install mkdir -p %{buildroot}%{rlibdir} %{_bindir}/R CMD INSTALL -l %{buildroot}%{rlibdir} %{packname} test -d %{packname}/src && (cd %{packname}/src; rm -f *.o *.so) rm -f %{buildroot}%{rlibdir}/R.css # remove buildroot from installed files find %{buildroot}%{rlibdir} -type f -exec sed -i "s@%{buildroot}@@g" {} \; %files %{rlibdir}/%{packname}