UTIdata {skewlmm} | R Documentation |
Data set for Unstructured Treatment Interruption Study
Description
Data set from a study of Unstructured Treatment Interruption in HIV-infected adolescents in four institutions in the USA. The main outcome is the HIV-1 RNA viral load, which is subject to censoring below the lower limit of detection of the assay (50 copies/mL). The censored observations are indicated by the variable RNAcens.
Usage
data(UTIdata)
Format
This data frame contains the following columns:
Patid
patient ID
Days.after.TI
days after treatment interruption
Fup
follow-up months
RNA
viral load RNA
RNAcens
censoring indicator for viral load
Details
This dataset was copied from the lmec
package, which was discontinued from CRAN in May 2022.
Source
Saitoh, A., Foca, M, et al. (2008), Clinical outcome in perinatally acquired HIV-infected children and adolescents after unstructured treatment interruption, Pediatrics,121, e513-e521.
See Also
Examples
library(ggplot2)
data(UTIdata)
ggplot(UTIdata) + geom_line(aes(x=Fup, y=log10(RNA), group=Patid)) +
geom_hline(yintercept=log10(50), color="red", linetype="dashed") +
geom_hline(yintercept=log10(400), color="red", linetype="dashed") +
labs(x="Time", y=bquote(log["10"]("RNA"))) + theme_bw()
# Proportion of censoring
prop.table(table(UTIdata$RNAcens))