%global __brp_check_rpaths %{nil} %global __requires_exclude ^libmpi %global packname simFastBOIN %global packver 2.0.0 %global rlibdir /usr/local/lib/R/library Name: R-CRAN-%{packname} Version: 2.0.0 Release: 1%{?dist}%{?buildtag} Summary: Fast Simulation of Bayesian Optimal Interval Designs for Phase I Trials License: MIT + file LICENSE URL: https://cran.r-project.org/package=%{packname} Source0: %{url}&version=%{packver}#/%{packname}_%{packver}.tar.gz BuildRequires: R-devel >= 3.5.0 Requires: R-core >= 3.5.0 BuildRequires: R-CRAN-Rcpp >= 1.0.0 BuildRequires: R-stats BuildRequires: R-utils Requires: R-CRAN-Rcpp >= 1.0.0 Requires: R-stats Requires: R-utils %description Design and evaluate phase I dose-finding trials that use the Bayesian optimal interval (BOIN) design of Liu and Yuan (2015) . Functions are provided to tabulate the decision boundaries, to simulate trials, to estimate the dose-toxicity curve under a monotonicity constraint and to select the maximum tolerated dose. The simulation engine is written in C++ and draws one random variate per patient in enrollment order, which reproduces the reference implementation in the 'BOIN' package trial by trial for a given seed. The traditional 3+3 design is provided as a comparator, with operating characteristics obtained in closed form rather than by simulation. %prep %setup -q -c -n %{packname} # fix end of executable files find -type f -executable -exec grep -Iq . {} \; -exec sed -i -e '$a\' {} \; # prevent binary stripping [ -d %{packname}/src ] && find %{packname}/src -type f -exec \ sed -i 's@/usr/bin/strip@/usr/bin/true@g' {} \; || true [ -d %{packname}/src ] && find %{packname}/src/Make* -type f -exec \ sed -i 's@-g0@@g' {} \; || true # don't allow local prefix in executable scripts find -type f -executable -exec sed -Ei 's@#!( )*/usr/local/bin@#!/usr/bin@g' {} \; %build %install mkdir -p %{buildroot}%{rlibdir} %{_bindir}/R CMD INSTALL -l %{buildroot}%{rlibdir} %{packname} test -d %{packname}/src && (cd %{packname}/src; rm -f *.o *.so) rm -f %{buildroot}%{rlibdir}/R.css # remove buildroot from installed files find %{buildroot}%{rlibdir} -type f -exec sed -i "s@%{buildroot}@@g" {} \; %files %{rlibdir}/%{packname}