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#include "TsParameterManager.hh"

#include "TsParallelSerialModel.hh"

#include <vector>
#include <math.h>

TsParallelSerialModel::TsParallelSerialModel(TsParameterManager* pM, G4String parmName)
: TsVOutcomeModel(pM, parmName), fPm(pM), fModelName("ParallelSerial")
{
	fS = fPm->GetUnitlessParameter(GetFullParmName(fModelName, "s"));
	fGamma = fPm->GetUnitlessParameter(GetFullParmName(fModelName, "gamma"));
	fTD50 = fPm->GetUnitlessParameter(GetFullParmName(fModelName, "TD50"));
}


TsParallelSerialModel::~TsParallelSerialModel() {;}


G4double TsParallelSerialModel::Initialize(std::vector<G4double> dose, std::vector<G4double> volume) {
	G4double totalVolume = SumElementsOfVector(volume);
	G4double NTCP = 1.0;

	// Based on Kallman, Agren and Brahme "Tumor and normal tissue responses to fractionated non-uniform dose delivery"
	G4double e = 2.718281828459045;
	for ( int i = 0; i < int(dose.size()); i++ ) {
		G4double P_1_D = pow( 2.0, -exp( e * fGamma * ( 1.0 - dose[i]/fTD50)));
		G4double argument = 1.0 - pow(P_1_D, fS);
		NTCP *= pow( argument, volume[i]/totalVolume );
	}

	NTCP = 100 * pow(1 - NTCP, 1./fS);
	return NTCP;
}
